Prevalence of urogenital tract infections with Ureaplasma urealyticum or HPV among men of reproductive age and the associated factors / 中华男科学杂志

Objective@#To investigate the prevalence of urogenital tract infections with Ureaplasma urealyticum (UU) and human papilloma virus (HPV) in males of reproductive age and the associated factors.@*METHODS@#Using the multi-stage cluster sampling method and a structured questionnaire, we conducted an investigation among 18－50 years old males in Songjiang District, Shanghai, from August 2016 to July 2018. We collected secretory specimens from the urogenital tract of the subjects and detected the infections of UU and HPV by laboratory examination.@*RESULTS@#Among the 621 males included in this study, 279 (44.93%) were found infected with UU, 18 (2.90%) with HPV, and 15 (2.42%) with both UU and HPV. Univariate analysis showed that smokers had a higher rate of UU infection (50.54% ［140/277］) than non-smokers (40.41 ［139/344］), and those with senior high school or secondary technical school education had a higher rate of HPV infection (4.84% ［12/248］) than others (1.61% ［6/373］). Binary stepwise logistic regression analysis revealed a higher risk of UU infection in the subjects with junior high school or lower education than in others (OR = 0.61, 95% CI: 0.39－0.96) as well as in smokers than in non-smokers (OR = 1.46, 95% CI: 1.01－2.01).@*CONCLUSIONS@#The prevalence of UU infection is high, while that of HPV is low among men of reproductive age in Songjiang, Shanghai. The screening of UU infection should be enhanced among men of reproductive age, especially among smokers and those with lower education.

The status and tendency projection of contraceptive status in China,Japan, India, South Africa and the United States of America from 1970 to 2030 / 复旦学报（医学版）

Objective To provide a basis to satisfy the need for family planning of women of reproductive age,according to the analysis and estimation of family planning status of married or in union women of reproductive age among China,Japan,India,South Africa and the United States of America.Methods U test and Chi-square test were applied to analyze the current situation (1970-2016) and tendency (2017-2030) of family planning indicators of the five countries from 1970 to 2030,which were selected from open database of World Contraceptive Use 2016.Results Compared with the family planning status in 1970,there was a significant change in total demand for family planning,contraceptive prevalence and unmet need for family planning (P＜0.001).To be specific,in 2016,contraceptive prevalence of married or in-union women of reproductive age in China,Japan,India,South Africa and the United States of America was 83.35％,59.9％,56.4％,64.9％ and 73.7％,respectively;unmet need for family planning was 3.8％,13.1％,15.5％,12.2％ and 7.2％,respectively.Besides,contraceptive methods composition in the five countries were changed in 2016 (P＜0.001) and the prevalence of modern methods was higher than traditional methods.Meanwhile,the percentage of demand for family planning satisfied with modern methods were increasing from 1970 to 2016.On the other hand,the projections of total demand for family planning,contraceptive prevalence,unmet need for family planning,composition of contraceptive methods and unmet need for modern methods would change from 2017 to 2030 (P＜0.001).It was estimated that,in 2030,China would have the largest number of people using contraceptive methods and India would have the largest number of people with unmet need for family planning.Moreover,China and India might be the countries with most users of modern methods,and India might be associated with the most users of traditional methods.Conclusions Considering current and projected status of huge total demand for family planning,high contraceptive prevalence,low unmet need for family planning,it is essential to supply approximate contraceptive methods.

The influence of high birth weight on the blood pressure during childhood—a cohort study / 中华流行病学杂志

Objective To explore the effects of high birth weight (HBW) on blood pressure (BP) during childhood.Methods A total of 1435 couples with high or normal birth weight were selected from a birth cohort who were born between 1993 and 1995 in Wuxi,China and,followed between 2005 and 2007.A questionnaire survey was conducted,with their height,weight and blood pressure measured.Results The medians of systolic blood pressure (SBP) and diastolic BP (DBP)of HBW group were 100 mm Hg (Q1-Q3∶90-110 mm Hg),64 mm Hg (Q1-Q3∶60-70 mm Hg) in the high birth weight group,respectively,while they were 100 mm Hg (Q1-Q3∶90-108 mm Hg),62 mm Hg (Q1-Q3∶60-70 mm Hg) in the normal weight group.No statistical significant difference was found between the exposed and unexposed groups.The proportion of elevated BP,including prehypertension and hypertension,in exposed group was 13.66％,a bit higher than that (11.57％) of the unexposed group (P ＝ 0.055).The relative risk (RR) of HBW on elevated BP was 1.06 (0.92-1.21),after adjusted the following parameters as BMI in childhood,sex,age during the follow-up period,age of mother at delivery,gestational age,type of feeding at infancy,dietary habit as well as the frequencies of exercise during childhood.Conclusion No statistically significant correlation was found between high birth weight and blood pressure of children.

The influence of smoking on the routine parameters of semen quality / 中华流行病学杂志

Objective To explore the effect and heaviness of smoking on the routine parameters of semen quality.Methods A total of 727 eligible subjects including 421 smokers and 306 nonsmokers were selected in 2004-2006 in Hebei,Shanxi,Guizhou,Zhejiang and Shandong provinces.Data on background information,general demographic characteristics,exposure to smoking and related confounding factors were obtained through a questionnaire survey.Semen samples of all the subjects were collected during the period of study.Parameters of semen were examined according to the manual recommended by WHO.Results Four models from the multiple logistic regression regarding the semen routine parameters were used as the dependent variables to be fitted in descending order respectively,while six confounders including area,age,abstinence time,education level,history of alcohol intake and the exposure to pesticides atc.,were adjusted.Results showed that smoking could affect the sperm viability,with significantly higher proportion of abnormal sperm viability seen in the smoking group (OR= 1.77,95％ CI:1.12-2.80).Proportions regarding the abnormal mobility and morphology of sperms in the smoking group were also significantly higher than in the control group,with OR values as 1.51 (95％CI:1.00-2.27) and 2.55 (95％CI:1.68-3.88) respectively.The density of sperms was significantly decreased in the smoking groups who smoked more than 20 cigarettes per day (OR= 1.70,95％CI:1.05-2.76) or the total numbers of cigarette consumption exceeding 150 000(OR=1.84,95％CI:1.03-3.29).Conclusion Smoking showed adverse effects on the quality of semens,especially for heavy or long-term smokers.

Do reproductive hormones explain the association between body mass index and semen quality? / 亚洲男科学杂志(英文版)

<p><b>AIM</b>To examine whether reproductive hormones play a role in the association between body mass index (BMI) and semen quality.</p><p><b>METHODS</b>Semen quality and testosterone (T), luteinizing hormone (LH), follicle-stimulating hormone (FSH) and estradiol (E(2)) were evaluated in 990 fertile males with age 38.9 +/- 9.7 (mean +/- SD) years recruited from the Chinese general population in 2001 and 2002.</p><p><b>RESULTS</b>Semen quality was reduced among underweight (BMI < 18.5) compared with normal (BMI 18.5-24.9) and overweight (BMI 25.0-29.9), but the associations were independent of reproductive hormones. After adjustment for the potential confounders, underweight men had reductions in sperm concentration (22.4 X 10(6)/mL), total sperm count (52.9 X 10(6)) and percentage of normal sperm forms (6.9%) compared with men with normal BMI. Being underweight may be a risk factor for low sperm concentration (OR: 4.68, 95% confidence intervals [CI]: 2.01-10.91). Otherwise, being overweight may be a protected factor for low sperm concentration (OR: 0.25; 95% CI: 0.08-0.83) and low total sperm count (OR: 0.37, 95% CI: 0.15-0.87).</p><p><b>CONCLUSION</b>Low BMI was associated with reduced semen quality. The associations between BMI and semen quality were found statistically significant even after adjustment for reproductive hormones. Reproductive hormones cannot explain the association between BMI and semen quality.</p>

Do Ureaplasma urealyticum infections in the genital tract affect semen quality? / 亚洲男科学杂志(英文版)

<p><b>UNLABELLED</b>To investigate the relationship between Ureaplasma urealyticum (UU) infection and semen quality.</p><p><b>METHODS</b>From 2001 to 2003, 346 eligible patients aged 20-45 years were invited from two hospitals in Shanghai, China, to participate in an investigation which included questionnaires about general and reproductive health, an external genital tract examination, UU culture and semen analysis. Multiple linear regression models were used to examine whether UU had a significant effect on semen quality after adjustment for confounding factors.</p><p><b>RESULTS</b>Findings suggested that UU infection was associated with higher semen viscosity and lower semen pH value. Sperm concentration was lower in UU positive subjects than that in UU negative subjects (54.04 X 10(6)/mL vs.70.58 X 10(6)/mL). However, UU did not significantly affect other semen quality indexes.</p><p><b>CONCLUSION</b>UU infection of the male genital tract could negatively influence semen quality.</p>

Does exposure to computers affect the routine parameters of semen quality? / 亚洲男科学杂志(英文版)

<p><b>AIM</b>To assess whether exposure to computers harms the semen quality of healthy young men.</p><p><b>METHODS</b>A total of 178 subjects were recruited from two maternity and children healthcare centers in Shanghai, 91 with a history of exposure to computers (i.e., exposure for 20 h or more per week in the last 2 years) and 87 persons to act as control (no or little exposure to computers). Data on the history of exposure to computers and other characteristics were obtained by means of a structured questionnaire interview. Semen samples were collected by masturbation in the place where the semen samples were analyzed.</p><p><b>RESULTS</b>No differences in the distribution of the semen parameters (semen volume, sperm density, percentage of progressive sperm, sperm viability and percentage of normal form sperm) were found between the exposed group and the control group. Exposure to computers was not found to be a risk factor for inferior semen quality after adjusting for potential confounders, including abstinence days, testicle size, occupation, history of exposure to toxic substances.</p><p><b>CONCLUSION</b>The present study did not find that healthy men exposed to computers had inferior semen quality.</p>

Epidemiological study on semen quality of 562 volunteers aged 22-30 / 中华流行病学杂志

<p><b>OBJECTIVE</b>This study is to understand the difference of semen quality among the different areas and the related factors.</p><p><b>METHODS</b>Five hundred and sixty-two people were under from seven provinces.</p><p><b>RESULTS</b>Results showed that the quantity and density of semen, the rate of moving forward semen, livability, percent age of normal formed semen and the total number of semen were statistically different among the seven areas. The difference was ranged as 28.82%, with the highest 2.95 ml in Shanxi province and the lowest 2.29 ml in Henan province. Geometric mean of semen density was found the lowest 36.27 x 10(6)/ml in Guizhou province, next to it was 42.52 x 10(6)/ml in Shandong province and the highest was 74.77 x 10(6)/ml in Hebei province. The percent age with forward progression of semen was seen the lowest 44.40% in Henan province, followed by 51.88% in Hebei province and 52.88% in Zhejiang province and the highest were 76.50% in Shanghai, 75.24% in Shanxi province, with a range of 72.30%. The highest semen viability was 85.89% in Shanghai, while the lowest 72.35% in Henan, with a range of 18.71%. Normal sperm morphology was seen the lowest 68.45% in Hebei province, with the highest 88.06% in Guizhou province, and the range was 28.65%. The geometric mean of total sperm count was seen the highest 204.23 x 10(6)/ml in Hebei province and the lowest 77.69 x 10(6)/ml in Guizhou province. Results showed through analysis of variance that some indexes were different in some provinces.</p><p><b>CONCLUSION</b>The results indicated that the semen quality was different in different regions in China and its influential factors may be region and geography environment.</p>